Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5275759 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
An efficient and practical synthesis of various aryl tetrafluoroethyl ethers by the reaction of phenols with 1,2-dibromotetrafluoroethane and the subsequent reduction with zinc dust was described. The nucleophilic substitution of 1,2-dibromotetrafluoroethane with phenols initiated by bromophilic attack was improved by using Cs2CO3 as a base and DMSO as a solvent.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jianqing Li, Jennifer X. Qiao, Daniel Smith, Bang-Chi Chen, Mark E. Salvati, Jacques Y. Roberge, Balu N. Balasubramanian,