| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275896 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
Design of novel phosphonium ionic liquids that are compatible with Grignard reagents have been investigated; several types of phosphonium salts that have an alkyl ether moiety have been synthesized and their capability evaluated as solvents for Grignard reagents. It has been established that even basic aliphatic Grignard reagent-mediated reactions are possible when methoxyethyl(tri-n-butyl)phosphonium bis(trifluoromethanesulfonyl)imide is used as the solvent.
Graphical abstractIntroduction of an alkyl ether moiety on the side arm of a phosphonium salt ionic liquid was quite effective in improving the capability of phosphonium salt ionic liquids as solvents for the Grignard reaction.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Toshiyuki Itoh, Keisuke Kude, Shuichi Hayase, Motoi Kawatsura,