| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275928 | Tetrahedron Letters | 2007 | 5 Pages |
Abstract
Exposure of a range of 3-hydroxy-2-sulfonylamino-4-alkynes to excess iodine delivers good yields of a series of iodopyrroles. Unexpectedly, the hydroxyl-dihydropyrroles, which were assumed to be the first-formed intermediates, turn out to be stable entities which have been isolated for the first time.
Graphical abstractA series of alkynyl sulfonamides have been smoothly converted into the corresponding iodopyrroles, useful as precursors to highly substituted derivatives. The intermediate hydroxydihydropyrroles, surprisingly, proved to be stable, isolable compounds.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
David W. Knight, Heinz C. Rost, Christopher M. Sharland, Jirada Singkhonrat,