| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275955 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
Novel spiroborate esters derived nonracemic 1,2-aminoalcohols and ethylene glycol are reported as highly effective catalysts for the asymmetric borane reduction of a variety of prochiral ketones with borane-dimethyl sulfide complex at room temperature. Optically active alcohols were obtained in excellent chemical yields using 0.1-10 mol % of catalysts with up to 99% ee.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Viatcheslav Stepanenko, Melvin De Jesús, Wildeliz Correa, Irisbel Guzmán, Cindybeth Vázquez, Wilanet de la Cruz, Margarita Ortiz-Marciales, Charles L. Barnes,