Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5276003 | Tetrahedron Letters | 2012 | 5 Pages |
Abstract
A straightforward method has been developed for the synthesis of 1-amidomethyl-imidazo[1,2-a]pyridines by Yb(OTf)3 catalyzed three-component reaction of aldehydes, acetamide, and imidazo[1,2-a]pyridines. A series of substituted 3-substituted imidazo[1,2-a]pyridines were synthesized in moderate to good yield (21-74%) under mild reaction condition and the catalyst was recycled for four cycles.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kasiviswanadharaju Pericherla, Bharti Khungar, Anil Kumar,