| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5276061 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
The direct palladium-catalyzed coupling reaction of indoles with alkynyl bromides was described in this paper. In the presence of catalytic amount of PdCl2(PPh3)2 and 2.0 equiv. NaOAc, the coupling reaction of indoles with alkynyl bromides proceeded smoothly at 50 °C to give the corresponding 3-alkynylindoles with high regioselectivity in good to excellent yields.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yonghong Gu, Xue-min Wang,