| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5276161 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
In this Letter the synthesis of benzospiro-indolizidinepyrrolidinones is described by a domino atom transfer radical cyclization reaction using a copper catalyst. The structure of one of the products was established by single crystal X-ray diffraction. The investigated precursors, bearing a homo allyl substituent on the N-indole, result in a 5-exo-trig, followed by a 6-endo-trig cyclization. When the N-indole is substituted with an allyl group, only the spiro-cyclization occurs.
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Physical Sciences and Engineering
Chemistry
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