| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5276174 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
The FeCl3-catalyzed C3-selective Friedel-Crafts alkylation of indoles using allylic, benzylic and propargylic alcohols has been developed. The reaction was performed in the presence of a catalytic amount of inexpensive anhydrous FeCl3 (10 mol %) in nitromethane under mild conditions. This method can also be used for the alkylation of pyrrole.
Graphical abstractThe FeCl3-catalyzed C3-selective Friedel-Crafts alkylation of indoles using allylic, benzylic and propargylic alcohols has been developed.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Umasish Jana, Sukhendu Maiti, Srijit Biswas,