| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5276177 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
A stereoselective synthesis of herbarumin-I in 22% overall yield, starting from l-ascorbic acid derived (S)-2,3-O-isopropylidine glyceraldehyde as a chiral template is reported. Stereoselective allylation and vinylation to control the required stereogenic centres and macrolactonisation followed by a ring-closing metathesis (RCM) are the key steps.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
K. Nagaiah, D. Sreenu, R. Srinivasa Rao, J.S. Yadav,