| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5276192 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
An efficient and convenient strategy for the enantioselective synthesis of enantiomerically enriched umbelactones is described utilizing a lipase-mediated resolution protocol, Baylis-Hillman reaction and ring closing metathesis as key steps. The lipase-resolution is carried out using several lipases from various sources in different solvents to afford the required intermediate 8 in good yield and high enantioselectivity.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ahmed Kamal, Tadiparthi Krishnaji, P. Venkat Reddy,