| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5276216 | Tetrahedron Letters | 2012 | 4 Pages |
Extension of the Chan-Lam N-alkylation of anilines by using alkylboranes as organoboron partners is reported. Alkylboranes, synthesized by hydroboration of styrenes, are effectively coupled with anilines, which comprises a facile method for the synthesis of highly functionalized phenethylaniline derivatives. This is the first time that alkylboranes are used in C-N copper-promoted cross-coupling reactions.
Graphical abstractExtension of the Chan-Lam N-alkylation of anilines by using alkylboranes as organoboron partners is reported. Alkylboranes, synthesized by hydroboration of styrenes, are effectively coupled with anilines, which comprises a facile method for the synthesis of highly functionalized phenethylaniline derivatives. This is the first time that alkylboranes are used in C-N copper-promoted cross-coupling reactions.Download full-size image
