Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5276242 | Tetrahedron Letters | 2012 | 5 Pages |
Abstract
A straightforward, mild, efficient, and general method has been developed for the synthesis of α-aminonitriles via Strecker reaction starting from aldehydes or ketones, amines, and trimethylsilyl cyanide in the presence of sulfated tungstate as a heterogeneous mild solid acid catalyst at room temperature and solvent free condition. The developed method has been successfully applied for the synthesis of a wide range of α-aminonitriles with variable functionality.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sagar P. Pathare, Krishnacharya G. Akamanchi,