Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5276277 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
Trifluoroethanol is found to be an efficient and recyclable medium in promoting one-pot, three-component coupling reactions of aldehydes or ketones, amines and trimethylsilyl cyanide or trimethyl phosphite to afford the corresponding α-amino nitriles or α-amino phosphonates in high yields. This protocol does not require the use of an acid or base catalyst.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Akbar Heydari, Samad Khaksar, Mahmood Tajbakhsh,