Native silica nanoparticle catalyzed anti-Markovnikov addition of thiols to inactivated alkenes and alkynes: a new route to linear and vinyl thioethers

A new route for the synthesis of linear and vinyl thioethers has been demonstrated using bare silica nanoparticle as catalyst at room temperature under solvent-free conditions. The catalyst can be reused up to six times without loss of catalytic activity.

Graphical abstractA new route for the synthesis of thioethers and vinyl thioethers has been demonstrated using silica nanoparticles as catalyst under solvent-free conditions. The catalyst can be reused up to six times without loss of catalytic activity.Download full-size image