A one-pot combination of amine and heterocyclic carbene catalysis: direct asymmetric synthesis of β-hydroxy and β-malonate esters from α,β-unsaturated aldehydes

The one-pot combination of amine and heterocyclic carbene catalysis (AHCC) enabled the synthesis of β-hydroxy, β-malonate and β-amino esters from α,β-unsaturated aldehydes with high enantioselectivity (91-97% ee).

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