| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5276378 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
Dimethylformamide, dimethylacetamide and tetramethylguanidine were found to act as increasingly active catalysts for the bromolactonisation of γ,δ- and δ,ε-unsaturated carboxylic acids with N-bromosuccinimide. The catalysts are readily removed in the work-up by washing with water to provide the pure bromolactone products without the need for column chromatography. Catalysis of the intermolecular bromoacetoxylation of alkenes with acetic acid and NBS by TMG was also demonstrated.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Simon M. Ahmad, D. Christopher Braddock, Gemma Cansell, Stephen A. Hermitage,