Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5276423 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
The synthesis of a variety of novel benzisoxazolo[2,3-a]pyridinium tetrafluoroborates is described. These compounds are conveniently prepared from pyridine N-oxide via a microwave-promoted palladium-catalyzed direct arylation of pyridine N-oxide with 2-bromoacetanilides to give 2-(2-acetamidoaryl)pyridine N-oxides, followed by hydrolysis, diazotization, and intramolecular displacement of nitrogen which affords the target benzisoxazolo[2,3-a]pyridinium tetrafluoroborates.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jeffery T. Myers, James M. Jr.,