Article ID Journal Published Year Pages File Type
5276486 Tetrahedron Letters 2008 5 Pages PDF
Abstract

A convenient and efficient procedure for the Friedel-Crafts acylation of aromatic compounds with carboxylic acids in the presence of P2O5/SiO2 is described. Both aromatic and aliphatic carboxylic acids reacted easily to afford the corresponding aromatic ketones. The use of non-toxic and inexpensive materials, simple and clean work-up, short reaction times and good yields of the products are the advantages of this method.

Graphical abstractA convenient and efficient procedure for the Friedel-Crafts acylation of aromatic compounds with carboxylic acids in the presence of P2O5/SiO2 is described.Download full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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