| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5276489 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
Oxidative carbon-carbon bond cleavage of N-alkoxycarbonylated cyclic amines was accomplished by NaNO2 in TFA to afford Ï-amino carboxylic acid in high yield. Optically active 3-hydroxypiperidine derivatives and 3-pipecolinate were converted to enantiomerically pure (R)-4-amino-3-hydroxybutanoic acid (GABOB) and (S)-2-pyrrolidone-4-carboxylate, respectively.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Osamu Onomura, Atsushi Moriyama, Kazuhiro Fukae, Yutaka Yamamoto, Toshihide Maki, Yoshihiro Matsumura, Yosuke Demizu,