| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5276563 | Tetrahedron Letters | 2007 | 5 Pages |
A new room temperature ionic liquid (IL) (2-hydroxyethyl)-trimethyl-ammonium (S)-2-pyrrolidinecarboxylic acid salt ([Choline][Pro]) has been synthesized from biorenewable and nontoxic raw materials (choline chloride and l(â)-proline) in a simple and relative green route. The IL has been demonstrated to be the efficient catalyst of the direct aldol reactions between ketones and aromatic aldehydes in water at room temperature. The aldol products can be obtained with good yields and the IL in aqueous phase can be separated easily and reused.
Graphical abstractA new functional ionic liquid (2-hydroxyethyl)-trimethyl-ammonium (S)-2-pyrrolidinecarboxylic acid salt ([Choline][Pro]) has been synthesized from biorenewable raw materials through a green chemistry route. It can be used to catalyze direct aldol reactions efficiently in water, and reused easily.Download full-size image
