Article ID Journal Published Year Pages File Type
5276654 Tetrahedron Letters 2007 4 Pages PDF
Abstract

Homoallylic alcohols, carbonyl compounds and nitriles undergo a smooth tandem Prins-Ritter type cyclization in the presence of CeCl3·7H2O/AcCl at ambient temperature to produce 4-amido tetrahydropyrans in high yields with all cis-selectivity. Spirocyclic 4-amido tetrahydropyrans are obtained in the case of cyclic ketones.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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