| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5276706 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
An efficient, mild and transition-metal-free method for the N-arylation of acetanilides, leading to a range of unsymmetrical diarylamine products is reported. Reactions of ortho-silylaryl triflates with acetanilides in the presence of tetrabutylammonium triphenyldifluorosilicate (TBAT) in toluene afforded the desired products in good to excellent yields. Regioselectivity was also observed when unsymmetrical aryne precursors were used.
Graphical abstractDownload full-size image
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
James C. Haber, Michael A. Lynch, Stacey L. Spring, Anthony D. Pechulis, Joseph Raker, Yi Wang,