Article ID Journal Published Year Pages File Type
5276715 Tetrahedron Letters 2011 4 Pages PDF
Abstract

The hydroacylation reaction of aldehydes with azodicarboxylates catalyzed by copper(II) acetate monohydrate has been reported. The reaction of various aldehydes gave the corresponding hydroacylation products in 60-98% yields under mild conditions. The method is simple, economical, and has practical advantages for the construction of the carbon-nitrogen bonds.

Graphical abstractLigand free copper-catalyzed hydroacylation reaction of aldehydes with azodicarboxylates was carried out in good to excellent yields under mild conditions. Especially, aromatic aldehydes were good substrates for this reaction. The method is simple, economical, and has practical advantages for the construction of carbon-nitrogen bonds.Download full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
, , , ,