Article ID Journal Published Year Pages File Type
5276780 Tetrahedron Letters 2008 5 Pages PDF
Abstract

The synthesis of 4-amidotetrahydropyrans has been achieved by a single-step Sakurai-Prins-Ritter reaction sequence in a domino fashion by the reaction of an aldehyde and allyltrimethylsilane in acetonitrile using Bi(OTf)3 as catalyst. The present synthesis is highly efficient and diastereoselective.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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