| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5276915 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
A new method was developed to synthesize highly functionalized lactams via a one pot reductive amination/lactam formation reaction. This methodology is amenable for parallel synthesis and was used to prepare a large number of lactam analogs in a library format with good ee (de) retention.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Martha A. Ornelas, Javier Gonzalez, Neal W. Sach, Paul F. Richardson, Kevin D. Bunker, Angelica Linton, Susan E. Kephart, Mason Pairish, Chuangxing Guo,