| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5276966 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
A series of 6-aminopyrimidines are cyanoacetylated with a mixture of cyanoacetic acid and acetic anhydride. When pyrimidin-4(3H)-ones are used as substrates, the substitution occurs at C-5, however, when the substrates are substituted pyrimidines at the C-2 and C-4, the cyanoacetylation takes place at the exocyclic amino group.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jairo Quiroga, Jorge Trilleras, Jaime Gálvez, Braulio Insuasty, Rodrigo AbonÃa, Manuel Nogueras, Justo Cobo, Antonio Marchal,