| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5277029 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
The tropos (chirally flexible) or atropos (chirally rigid) nature of BIPHEP-Rh complexes critically depends on amines and alcohols complexed. The BIPHEP-Rh complex with aminoalcohol NOBIN is significantly tropos and can be chirally controlled by aminoalcohol NOBIN instantaneously even at room temperature. The BIPHEP-Rh/NOBIN complex thus controlled can be used as an asymmetric catalyst to give higher enantioselectivity (up to 98% ee) and yield in ene-type cyclization of 1,6-enynes without use of acid.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Koichi Mikami, Shohei Kataoka, Kazuki Wakabayashi, Kohsuke Aikawa,