| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5277036 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
Substituted 4,4-diaryl-3-butenyl-1-amines are synthesized in nearly 34-47% overall yields starting from 3-hydroxypiperidine by the regioselective Baeyer-Villiger lactonization, Grignard addition and elimination sequence. This facile strategy was also used to synthesize racemic SKF 89976A.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Meng-Yang Chang, Si-Yun Wang, Chun-Li Pai,