| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5277165 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
A wide range of alcohols 2 react with various allenes 1 in the presence of ClAuPPh3/AgOTf catalyst at ambient temperature without solvent to produce allylic ethers 3. Contrary to the hydroamination, which proceeds through high chiral-face selectivity for chiral allenes to give the corresponding chiral allylic amines, transfer of chirality is not observed in the hydroalkoxylation, suggesting that the mechanism of the gold-catalyzed hydroalkoxylation is different from that of hydroamination.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Naoko Nishina, Yoshinori Yamamoto,