Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5277262 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
The treatment of 2,3-epoxy primary alcohols with lead(IV) acetate (LTA) leads to α-acetoxy aldehydes or α-acetoxy ketones, through the nucleophilic ring-opening of an intermediate oxonium and the subsequent carbon-carbon bond cleavage. This reaction represents a new route to optically active α-hydroxy carbonyl compounds.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Enrique Alvarez-Manzaneda, Rachid Chahboun, Esteban Alvarez, Ramón Alvarez-Manzaneda, Pedro E. Muñoz, FermÃn Jiménez, Hanane Bouanou,