Article ID Journal Published Year Pages File Type
5277262 Tetrahedron Letters 2011 4 Pages PDF
Abstract

The treatment of 2,3-epoxy primary alcohols with lead(IV) acetate (LTA) leads to α-acetoxy aldehydes or α-acetoxy ketones, through the nucleophilic ring-opening of an intermediate oxonium and the subsequent carbon-carbon bond cleavage. This reaction represents a new route to optically active α-hydroxy carbonyl compounds.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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