Article ID Journal Published Year Pages File Type
5277292 Tetrahedron Letters 2010 4 Pages PDF
Abstract

A series of cis-locked stilbenic compounds related to combretastatin and combretastatin A4 has been designed and synthesized. The cytotoxic effects of these rigid analogues were evaluated as well as their abilities to inhibit tubulin polymerization.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry