Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5277333 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
A palladium-carbene catalyzed Sonogashira coupling of unactivated alkyl bromides with alkyl substituted alkynes is reported. For the first time, unactivated secondary alkyl halides were successfully employed in Sonogashira reactions.
Graphical abstractA palladium-carbene catalyzed Sonogashira coupling of unactivated alkyl bromides with alkyl substituted alkynes is reported.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gereon Altenhoff, Sebastian Würtz, Frank Glorius,