Article ID Journal Published Year Pages File Type
5277375 Tetrahedron Letters 2008 4 Pages PDF
Abstract

Ketones undergo smooth rearrangement with TMSN3 in the presence of FeCl3 under extremely mild conditions to provide the corresponding amides, imides and lactams in good yields with high selectivity. This method is very useful for the preparation of a wide range of amides, imides and lactams from ketones. The use of FeCl3 makes this method simple, convenient and cost-effective.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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