| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5277412 | Tetrahedron Letters | 2010 | 5 Pages |
Abstract
This protocol is for an expedient and operationally simple synthesis of allylic azides and one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles from homoallyl alcohols. Synthesis of allylic azides involves the palladium-catalyzed hydroazidation of unactivated olefins with migration of double bond. This hydroazidation can be coupled to Cu(I) promoted 1,3-dipolar cycloaddition to afford the corresponding 1,4-disubstituted 1,2,3-triazoles.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
P. Surendra Reddy, V. Ravi, B. Sreedhar,