| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5277456 | Tetrahedron Letters | 2011 | 5 Pages |
Abstract
Tetrahydro-2H-[2]benzopyrano[3,4-c]pyrrol-3-ones and the related 3a-methyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]isoindole analogues were synthesised by an intramolecular Diels-Alder reaction. The observed stereoselectivity was dependent upon the nature of the tethered dienophile as well as the judicious placement of the amide.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Stereoselective synthesis of tetrahydro-2H-[2]benzopyrano[3,4-c]pyrrol-3-ones and related compounds as precursors of serotonin 5-HT2C receptor agonists](/preview/png/5277456.png "First Page Preview: Stereoselective synthesis of tetrahydro-2H-[2]benzopyrano[3,4-c]pyrrol-3-ones and related compounds as precursors of serotonin 5-HT2C receptor agonists")
Authors
Stuart Francis, Takao Kiyoi, Mark Reid, Keneth Davies, Steven Laats, Duncan McArthur, Helen Feilden, Anna Marie Easson, Yasuko Kiyoi, Grant Wishart, Peter Ray,