Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5277474 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
A library of benzimidazoles, benzoxazoles, and benzothiazoles was efficiently synthesized by condensation of o-phenylenediamine, o-aminophenol, and o-aminothiophenol respectively with aromatic aldehydes in the presence of catalytic amounts of Animal Bone Meal (ABM) and Lewis acids doped ABMs. Reactions were conducted under reflux conditions in air. The remarkable features of this new protocol are high conversion, short reaction times, and cleaner reaction profiles, straightforward procedure, and reduction in catalyst toxicity.
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Authors
Yassin Riadi, Rachid Mamouni, Rachid Azzalou, Mohammadine El Haddad, Sylvain Routier, Gérald Guillaumet, Saïd Lazar,