Article ID Journal Published Year Pages File Type
5277476 Tetrahedron Letters 2011 6 Pages PDF
Abstract

A simple, efficient and general method has been developed for the one-pot three component syntheses of α-aminophosphonates. The condensation of aldehyde, amine and triethyl phosphite by employing CeO2 nanoparticles as catalyst gave α-aminophosphonates. The catalyst showed good recyclability. Nano CeO2 has been found to be an excellent catalyst for the green synthesis of α-aminophosphonates under ultrasound irradiation and solvent-free condition. The α-aminophosphonates are obtained in good to excellent yield. This catalyst provides cleaner conversion, short reaction time and high selectivity which makes the protocol feasible and economical attractive.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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