| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5277539 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
Two conjugates at the 7- and 10-positions of paclitaxel and 10-deacetyl-paclitaxel with polyamine spermine have been synthesized. The low cytotoxicity evaluated in MCF7 and MCF7-R cell lines suggests that these conjugates could act as potential prodrugs.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Arturo Battaglia, Andrea Guerrini, Eleonora Baldelli, Gabriele Fontana, Greta Varchi, Cristian Samorì, Ezio Bombardelli,