| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5277646 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
A chemoenzymatic access to thiol compounds, including ethyl 3-thiobutanoate, 3-thio-p-menthene and 8-thio-p-menthan-2-one, three compounds of interest in flavour and fragrance chemistry presenting various fruity notes, is proposed. It involves an indium(III)-catalysed hydrothioacetylation of renewable precursors followed by an enzymatic solvolysis of the obtained thioesters by lipases in aqueous or organic solvents.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Reine-Marie Dia, Rim Belaqziz, Abderrahmane Romane, Sylvain Antoniotti, Elisabet Duñach,