Article ID Journal Published Year Pages File Type
5277700 Tetrahedron Letters 2007 4 Pages PDF
Abstract

3-Alkylindoles undergo smooth oxidation with IBX in the presence of CeCl3·7H2O in aqueous acetonitrile at ambient temperature to afford the corresponding 3-hydroxyoxindoles in high yields. This method is very useful for the direct preparation of 3-hydroxyoxindoles from 3-alkylindoles. Operational simplicity, mild and neutral reaction conditions in aqueous solution are the key features of this protocol.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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