Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5277700 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
3-Alkylindoles undergo smooth oxidation with IBX in the presence of CeCl3·7H2O in aqueous acetonitrile at ambient temperature to afford the corresponding 3-hydroxyoxindoles in high yields. This method is very useful for the direct preparation of 3-hydroxyoxindoles from 3-alkylindoles. Operational simplicity, mild and neutral reaction conditions in aqueous solution are the key features of this protocol.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
J.S. Yadav, B.V. Subba Reddy, Ch. Suresh Reddy, A.D. Krishna,