Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5277716 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
An improved, efficient, and simple method for the synthesis of nonsymmetrical diamides of fumaric acid is reported. Starting from commercially available substrates, maleic diamides are formed in two steps, and then isomerized in a focused microwave reactor in acetonitrile as the solvent in the presence of a catalytic amount of piperidine, giving the corresponding fumaramides in high yields and purity.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Vita Majce, Marijan KoÄevar, Slovenko Polanc,