| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5277806 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
The total synthesis of the 2-azaanthraquinone alkaloid, scorpinone (4), isolated from the mycelium of a Bispora-like tropical fungus, has been completed in nine steps. The two key steps involve a microwave-assisted thermal electrocyclic reaction for the synthesis of an 8-oxygenated isoquinoline skeleton from a 1-aza 6Ï-hexatriene system, and a regioselective microwave-assisted [4+2] cycloaddition for the construction of a 2-azaanthraquinone framework.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Tominari Choshi, Teppei Kumemura, Junko Nobuhiro, Satoshi Hibino,