Article ID Journal Published Year Pages File Type
5277872 Tetrahedron Letters 2010 4 Pages PDF
Abstract

The FeCl2/K2CO3 catalyst system was developed successfully for the N-alkylation of sulfonamides with benzylic alcohols via borrowing hydrogen method. XPS analysis suggested a possible catalyst cycle between Fe(II) and Fe(0). Under the optimized condition, the scope of the protocol was demonstrated in 21 different alkylation reactions. High yields, in general >90%, are achieved in most cases.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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