| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5277993 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
The reaction of 1-[(2,4,6-triisopropylphenyl)sulfinyl]-2-naphthaldehyde with (trifluoromethyl)trimethylsilane using tetramethylammonium fluoride gave trifluoromethylated compounds in high yield with high diastereoselectivity. Desilylation and subsequent recrystallization yielded the enantiomerically and diastereomerically pure trifluoroethanol, which afforded chiral 1-(2-naphthyl)-2,2,2-trifluoroethanol after removal of the sulfinyl group.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hideki Sugimoto, Shuichi Nakamura, Yoshihiro Shibata, Norio Shibata, Takeshi Toru,