Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5278025 | Tetrahedron Letters | 2008 | 5 Pages |
Abstract
Alkenyl bromides were found to be useful reactants for the palladium-catalysed direct C-H activation/functionalisation reaction of heteroaromatics such as benzoxazole or benzothiazole. Moderate to good yields of coupling products were obtained using both α- and β-substituted alkenyl bromides or even the trisubstituted alkenyl bromide 2-bromo-3-methylbut-2-ene. This reaction is environmentally attractive as it provides only HX associated to the base as a by-product.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Aditya L. Gottumukkala, Fazia Derridj, Safia Djebbar, Henri Doucet,