| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5278048 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
The cross-metathesis of allylestrone with acrylic acid derivatives using homogeneous and heterogenized Ru-catalysts was evaluated for the synthesis of a new 17β-hydroxysteroid dehydrogenase type 1 inhibitor. Hoveyda-type catalyst containing an additional diethylamino group turned out to be comparably active as homogeneous Grubbs II catalyst after immobilization on an acidic ion exchange resin which greatly facilitated workup.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Andreas Kirschning, Kirsten Harmrolfs, Klaas Mennecke, Josef Messinger, Uwe Schön, Karol Grela,