| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5278103 | Tetrahedron Letters | 2011 | 5 Pages |
Abstract
An efficient, copper-free Sonogashira coupling reaction of 1-chloroisoquinolines and terminal alkynes, catalyzed by Pd(OAc)2/Ruphos, in the presence of Et3N and tetrahydrofuran leads to the formation of 1-alkynyl-3-substituted isoquinolines in good yields.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
K. Prabakaran, F. Nawaz Khan, Jong Sung Jin,