Article ID Journal Published Year Pages File Type
5278143 Tetrahedron Letters 2006 4 Pages PDF
Abstract

A mixture of cyclohexanone or 4-methylcyclohexanone and an aromatic aldehyde is treated with dimethylsulfoxonium methylide to effect a tandem aldol/epoxidation reaction. The resulting product contains three or four new stereocenters but only one of the possible four or eight diastereomers is formed.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry