| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5278145 | Tetrahedron Letters | 2006 | 5 Pages |
Abstract
We describe a facile synthetic method of carbamate- and urea-linked glycoconjugates using sugar carboxylic acids by the modified Curtius rearrangement. This reaction is a simple one-pot procedure, and various nucleophiles including tertiary alcohols can be utilized to afford desired compounds in moderate to high yields. And the stereospecific synthesis of the anomeric isomers is achieved using the corresponding two stereoisomers of glycosyl carboxylic acid.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Daisuke Sawada, Shinya Sasayama, Hideyo Takahashi, Shiro Ikegami,