| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5278284 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
The direct aldol addition of malonates to aromatic, hetero-aromatic and unsaturated aldehydes leading to β-hydroxymalonates is described. The stability of these products, the trimethyl silyl protection of the hydroxyl group as well as the role of both SiCl4 and i-Pr2EtN in attaining the final products are also discussed.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Antonio Massa, Arrigo Scettri, Rosanna Filosa, Laura Capozzolo,